Duquesne Family Office LLC
Duquesne Family Office LLC manages Duquesne Family Office LLC, an institutional investment manager registered with the SEC (CIK: 1536411). Portfolio data sourced from Form 13F filings.
Duquesne Family Office LLC managed $3.38 billion across 68 positions in Q1 2026, establishing 30 new holdings. NTRA dominated the firm’s concentrated bets at 18.1%, followed by EWZ (8.7%), INSM (5.6%), TSM (5.0%), and RSP (4.7%). This aggressive refresh suggests firm conviction, particularly within the top five holdings that capture over 42% of the capital.
Duquesne Family Office LLC (Duquesne Family Office LLC) — Top 10 Holdings Q1 2026
| Stock | Weight | Activity | Shares Δ | Value |
|---|---|---|---|---|
 NTRA Natera Inc | Add +22% | +552K | $612.7M | |
EWZ Ishares Inc | Reduce −51% | −7.90M | $294.2M | |
INSM Insmed Inc | Reduce −22% | −328K | $188.7M | |
Taiwan Semiconductor Manufac | Reduce −9% | −48K | $167.4M | |
RSP Invesco Exchange Traded Fd T | Reduce −30% | −353K | $157.6M | |
YPF Ypf Sociedad Anonima | Add +433% | +2.63M | $149.6M | |
TBBB Bbb Foods Inc | Add +16% | +434K | $110.0M | |
Alcoa Corp | Add +9% | +117K | $99.1M | |
NAMS Newamsterdam Pharma Company | Hold | — | $98.3M | |
Sea Ltd | Add +17% | +156K | $91.1M |
Duquesne Family Office LLC’s Implied Market View — Q1 2026
Last Quarter Activity — Duquesne Family Office LLC (Duquesne Family Office LLC) Q1 2026
| Stock | Action | Shares Δ | Value | Wt. |
|---|---|---|---|---|
YPF Ypf Sociedad Anonima | Add +433% | +2.63M | $149.6M | 4.43% |
NTRA Natera Inc | Add +22% | +552K | $612.7M | 18.14% |
STM Stmicroelectronics N V | Add +238% | +1.84M | $90.3M | 2.67% |
Broadcom Inc | New Buy | +196K new | $60.6M | 1.8% |
ARGT Global X Fds | New Buy | +387K new | $36.2M | 1.07% |
CAI Caris Life Sciences Inc | New Buy | +1.89M new | $33.9M | 1.0% |
RVMD Revolution Medicines Inc | New Buy | +316K new | $30.7M | 0.91% |
Sandisk Corp | New Buy | +38K new | $24.2M | 0.72% |
QoQ change vs Dec 2025 filing.
| Stock | Action | Shares Δ | Value | Wt. |
|---|---|---|---|---|
EWZ Ishares Inc | Reduce −51% | −7.90M | $294.2M | 8.71% |
INSM Insmed Inc | Reduce −22% | −328K | $188.7M | 5.59% |
Taiwan Semiconductor Manufac | Reduce −9% | −48K | $167.4M | 4.96% |
RSP Invesco Exchange Traded Fd T | Reduce −30% | −353K | $157.6M | 4.67% |
WWD Woodward Inc | Reduce −64% | −380K | $75.6M | 2.24% |
TEVA Teva Pharmaceutical Inds Ltd | Reduce −60% | −3.50M | $71.6M | 2.12% |
AEVA AEVA Aeva Technologies Inc | Full Exit | Sold 100% | $24.2M | 0% |
GOOG GOOGL Alphabet Inc | Full Exit | Sold 100% | $120.5M | 0% |
AAL AAL American Airls Group Inc | Full Exit | Sold 100% | $9.8M | 0% |
AGX AGX Argan Inc | Full Exit | Sold 100% | $9.4M | 0% |
QoQ change vs Dec 2025 filing.
New Positions — Duquesne Family Office LLC (Duquesne Family Office LLC) Q1 2026
Duquesne Family Office deployed $60.6 million into Broadcom Inc. stock during Q1 2026, marking its largest new purchase. The allocation reflects conviction in essential semiconductor infrastructure, crucial for artificial intelligence and data center expansion. Duquesne also committed $36.2 million to the Global X MSCI Argentina ETF (ARGT), signaling a targeted bet on the Latin American nation’s economic trajectory. Caris Life Sciences Inc. (CAI) captured a $33.9 million investment, staking a claim in advanced cancer diagnostics and precision medicine.
A distinct pattern defines Duquesne’s Q1 purchases. The firm committed capital to specific segments: foundational technology, advanced healthcare innovation, and targeted geographic macro exposure. Duquesne bought $30.7 million of Revolution Medicines Inc. (RVMD), further solidifying its biotech exposure. It also acquired $24.2 million in Sandisk Corp. (SNDK), confirming a strategic focus on storage hardware. Humana Inc. (HUM) captured $23.8 million, indicating an interest in managed healthcare services. These positions signal a selective approach, identifying concentrated value or growth opportunities across distinct industries.
| Stock | Action | Value |
|---|---|---|
Broadcom Inc | New Buy | $60.6M |
| See AVGO analyst sentiment | ||
ARGT Global X Fds | New Buy | $36.2M |
CAI Caris Life Sciences Inc | New Buy | $33.9M |
RVMD Revolution Medicines Inc | New Buy | $30.7M |
Sandisk Corp | New Buy | $24.2M |
| See SNDK analyst sentiment | ||
HUM Humana Inc | New Buy | $23.8M |
TWLO Twilio Inc | New Buy | $22.9M |
Jabil Inc | New Buy | $21.8M |
| See JBL analyst sentiment | ||
GSG Ishares S&P Gsci Commodity- | New Buy | $20.7M |
Linde Plc | New Buy | $20.4M |
| See LIN analyst sentiment | ||
STX Seagate Technology Hldngs Pl | New Buy | $19.9M |
NUVB Nuvation Bio Inc | New Buy | $19.5M |
Intel Corp | New Buy | $18.2M |
| See INTC analyst sentiment | ||
BLTE Belite Bio Inc Sponsored | New Buy | $16.9M |
Arm Holdings Plc | New Buy | $16.1M |
| See ARM analyst sentiment | ||
OLMA Olema Pharmaceuticals Inc | New Buy | $14.7M |
Q Qnity Electronics Inc | New Buy | $14.5M |
XENE Xenon Pharmaceuticals Inc | New Buy | $13.9M |
JBS Jbs N.V. | New Buy | $11.8M |
NET Cloudflare Inc | New Buy | $10.8M |
LYB Lyondellbasell Industries Nv | New Buy | $10.6M |
VIST Vista Energy S.A.B. De C.V. | New Buy | $10.2M |
TWST Twist Bioscience Corp | New Buy | $9.8M |
COHR Coherent Corp | New Buy | $9.6M |
CLS Celestica Inc | New Buy | $9.4M |
DBVT Dbv Technologies S A Sponsored | New Buy | $8.0M |
Micron Technology Inc | New Buy | $7.9M |
| See MU analyst sentiment | ||
LITE Lumentum Hldgs Inc | New Buy | $4.9M |
SOLS Solstice Advanced Matls Inc | New Buy | $4.8M |
WLK Westlake Corporation | New Buy | $2.5M |
Increased Positions — Duquesne Family Office LLC (Duquesne Family Office LLC)
Duquesne Family Office LLC focused capital on existing positions in Q1 2026. The firm increased its YPF stake by 433%, raising the holding to $149.6 million. Duquesne also grew its largest existing position, NTRA, adding 22% and pushing the investment to $612.7 million.
Firm’s other additions included a 16% increase in TBBB, now valued at $110.0 million. Duquesne raised its AA position by 9%, making that stake $99.1 million. Further, Duquesne added 17% to SE, bringing the holding to $91.1 million. These capital deployments across five existing companies illustrate a strategy of reinforcing successful bets.
| Stock | Action | Value |
|---|---|---|
NTRA Natera Inc | Add +22% | $612.7M |
YPF Ypf Sociedad Anonima | Add +433% | $149.6M |
TBBB Bbb Foods Inc | Add +16% | $110.0M |
Alcoa Corp | Add +9% | $99.1M |
Sea Ltd | Add +17% | $91.1M |
STM Stmicroelectronics N V | Add +238% | $90.3M |
ROKU Roku Inc | Add +29% | $71.0M |
OPCH Option Care Health Inc | Add +7% | $50.3M |
SCCO Southern Copper Corp | Add +1% | $21.0M |
CLF Cleveland-Cliffs Inc New | Add +33% | $19.5M |
U Unity Software Inc | Add +80% | $16.2M |
ADMA Adma Biologics Inc | Add +513% | $13.9M |
Stocks Sold or Reduced — Duquesne Family Office LLC (Duquesne Family Office LLC) Q1 2026
Duquesne Family Office LLC aggressively pruned its portfolio during Q1 2026, executing deep cuts across multiple sectors. Woodward Inc., an industrial player, suffered the deepest cut, a 64% reduction. Holdings in Teva Pharmaceutical Industries Ltd. also shrank considerably, down 60%. The institutional manager slashed its Ishares Inc EWZ stake by 51%, reducing exposure to emerging markets. Duquesne exited 30% of its Invesco Exchange Traded Fd T RSP shares, a move away from the equal-weight S&P 500. Insmed Inc., another pharmaceutical stock, saw a 22% reduction. Taiwan Semiconductor Manufacturing Co. position experienced a more modest 9% trim. These significant reductions indicate a concentrated shift in sector allocation, particularly from certain industrials and pharmaceuticals.
| Stock | Action | Δ Value | Shares Δ |
|---|---|---|---|
EWZ Ishares Inc | Reduce −51% | $294.2M | 7.90M |
INSM Insmed Inc | Reduce −22% | $188.7M | 328K |
Taiwan Semiconductor Manufac | Reduce −9% | $167.4M | 48K |
RSP Invesco Exchange Traded Fd T | Reduce −30% | $157.6M | 353K |
WWD Woodward Inc | Reduce −64% | $75.6M | 380K |
TEVA Teva Pharmaceutical Inds Ltd | Reduce −60% | $71.6M | 3.50M |
 Amazon Com Inc | Reduce −85% | $51.2M | 1.43M |
CPNG Coupang Inc | Reduce −61% | $50.4M | 4.11M |
CRH Crh Plc | Reduce −21% | $39.7M | 97K |
FIGR Figure Technology Solutio | Reduce −25% | $39.1M | 389K |
QSR Restaurant Brands Intl Inc | Reduce −62% | $33.6M | 755K |
LSCC Lattice Semiconductor Corp | Reduce −65% | $30.0M | 603K |
UAL United Airls Hldgs Inc | Reduce −25% | $24.2M | 86K |
WAB Wabtec | Reduce −68% | $23.7M | 205K |
IWM Ishares Tr | Reduce −65% | $19.6M | 147K |
BE Bloom Energy Corp | Reduce −82% | $18.5M | 604K |
DAKT Daktronics Inc | Reduce −34% | $11.0M | 290K |
STUB Stubhub Hldgs Inc | Reduce −41% | $8.5M | 939K |
PCT Purecycle Technologies Inc | Reduce −67% | $5.0M | 1.92M |
MELI Mercadolibre Inc | Reduce −94% | $4.8M | 44K |
Why Duquesne Family Office LLC’s (Duquesne Family Office LLC) Moves Matter
Duquesne Family Office LLC executed a significant Q1 2026 portfolio rotation. The institutional manager initiated 30 new positions during the quarter, signaling a distinct shift in its market outlook. Natera Inc. (NTRA) became its top holding, representing 18.1% of the portfolio with a $612.7 million valuation. The Brazil ETF (EWZ) captured 8.7%, or $294.2 million, indicating a conviction in specific emerging markets. Insmed Inc. (INSM) secured 5.6% at $188.7 million. These concentrated top bets in high-growth biotech and a volatile emerging economy suggest confidence in targeted speculative plays over broad market indices.
Retail investors frequently monitor 13F filings for insight into institutional moves. These documents disclose holdings 45 days after the quarter’s end. This delay means Duquesne’s Q1 2026 positions reveal its thinking as of March 31, 2026, not today. Traders considering mirroring these positions risk acting on outdated information. Market conditions or the fund’s internal strategy may have shifted dramatically since the filing date. Investors use these filings to identify potential investment themes or new companies for personal research, not as current trading signals.
About Duquesne Family Office LLC — Duquesne Family Office LLC
Duquesne Family Office LLC manages Duquesne Family Office LLC, an institutional investment manager registered with the SEC (CIK: 1536411). Portfolio data sourced from Form 13F filings.
- Manages Duquesne Family Office LLC — SEC-registered institutional investment manager
- CIK: 1536411 — Required to disclose equity holdings quarterly via Form 13F
Duquesne Family Office LLC (Duquesne Family Office LLC) — Complete Q1 2026 13F Holdings
| Stock | Weight | Activity | Shares Δ | Value |
|---|---|---|---|---|
NTRA Natera Inc | Add +22% | +552K | $612.7M | |
EWZ Ishares Inc | Reduce −51% | −7.90M | $294.2M | |
INSM Insmed Inc | Reduce −22% | −328K | $188.7M | |
Taiwan Semiconductor Manufac | Reduce −9% | −48K | $167.4M | |
RSP Invesco Exchange Traded Fd T | Reduce −30% | −353K | $157.6M | |
YPF Ypf Sociedad Anonima | Add +433% | +2.63M | $149.6M | |
TBBB Bbb Foods Inc | Add +16% | +434K | $110.0M | |
Alcoa Corp | Add +9% | +117K | $99.1M | |
NAMS Newamsterdam Pharma Company | Hold | — | $98.3M | |
Sea Ltd | Add +17% | +156K | $91.1M | |
STM Stmicroelectronics N V | Add +238% | +1.84M | $90.3M | |
WWD Woodward Inc | Reduce −64% | −380K | $75.6M | |
TEVA Teva Pharmaceutical Inds Ltd | Reduce −60% | −3.50M | $71.6M | |
ROKU Roku Inc | Add +29% | +167K | $71.0M | |
Broadcom Inc | New Buy | +196K new | $60.6M | |
SPY State Str Spdr S&P 500 Etf T | Hold | — | $58.5M | |
Amazon Com Inc | Reduce −85% | −1.43M | $51.2M | |
CPNG Coupang Inc | Reduce −61% | −4.11M | $50.4M | |
OPCH Option Care Health Inc | Add +7% | +123K | $50.3M | |
CRH Crh Plc | Reduce −21% | −97K | $39.7M | |
FIGR Figure Technology Solutio | Reduce −25% | −389K | $39.1M | |
ARGT Global X Fds | New Buy | +387K new | $36.2M | |
CAI Caris Life Sciences Inc | New Buy | +1.89M new | $33.9M | |
QSR Restaurant Brands Intl Inc | Reduce −62% | −755K | $33.6M | |
RVMD Revolution Medicines Inc | New Buy | +316K new | $30.7M | |
LSCC Lattice Semiconductor Corp | Reduce −65% | −603K | $30.0M | |
Sandisk Corp | New Buy | +38K new | $24.2M | |
UAL United Airls Hldgs Inc | Reduce −25% | −86K | $24.2M | |
HUM Humana Inc | New Buy | +138K new | $23.8M | |
WAB Wabtec | Reduce −68% | −205K | $23.7M | |
TWLO Twilio Inc | New Buy | +182K new | $22.9M | |
Jabil Inc | New Buy | +82K new | $21.8M | |
SCCO Southern Copper Corp | Add +1% | +1K | $21.0M | |
GSG Ishares S&P Gsci Commodity- | New Buy | +643K new | $20.7M | |
Linde Plc | New Buy | +41K new | $20.4M | |
STX Seagate Technology Hldngs Pl | New Buy | +51K new | $19.9M | |
IWM Ishares Tr | Reduce −65% | −147K | $19.6M | |
CLF Cleveland-Cliffs Inc New | Add +33% | +568K | $19.5M | |
NUVB Nuvation Bio Inc | New Buy | +4.54M new | $19.5M | |
BE Bloom Energy Corp | Reduce −82% | −604K | $18.5M | |
Intel Corp | New Buy | +411K new | $18.2M | |
BLTE Belite Bio Inc Sponsored | New Buy | +106K new | $16.9M | |
PTGX Protagonist Therapeutics Inc | Hold | — | $16.8M | |
U Unity Software Inc | Add +80% | +329K | $16.2M | |
Arm Holdings Plc | New Buy | +107K new | $16.1M | |
OLMA Olema Pharmaceuticals Inc | New Buy | +987K new | $14.7M | |
Q Qnity Electronics Inc | New Buy | +126K new | $14.5M | |
ADMA Adma Biologics Inc | Add +513% | +1.29M | $13.9M | |
XENE Xenon Pharmaceuticals Inc | New Buy | +239K new | $13.9M | |
JBS Jbs N.V. | New Buy | +656K new | $11.8M | |
DAKT Daktronics Inc | Reduce −34% | −290K | $11.0M | |
NET Cloudflare Inc | New Buy | +53K new | $10.8M | |
LYB Lyondellbasell Industries Nv | New Buy | +131K new | $10.6M | |
VIST Vista Energy S.A.B. De C.V. | New Buy | +135K new | $10.2M | |
TWST Twist Bioscience Corp | New Buy | +206K new | $9.8M | |
COHR Coherent Corp | New Buy | +40K new | $9.6M | |
CLS Celestica Inc | New Buy | +33K new | $9.4M | |
STUB Stubhub Hldgs Inc | Reduce −41% | −939K | $8.5M | |
DBVT Dbv Technologies S A Sponsored | New Buy | +383K new | $8.0M | |
Micron Technology Inc | New Buy | +23K new | $7.9M | |
SATS Echostar Corp | Hold | — | $7.1M | |
ALM Almonty Inds Inc | Hold | — | $6.8M | |
PCT Purecycle Technologies Inc | Reduce −67% | −1.92M | $5.0M | |
LITE Lumentum Hldgs Inc | New Buy | +7K new | $4.9M | |
MELI Mercadolibre Inc | Reduce −94% | −44K | $4.8M | |
SOLS Solstice Advanced Matls Inc | New Buy | +63K new | $4.8M | |
WLK Westlake Corporation | New Buy | +21K new | $2.5M | |
WVE Wave Life Sciences Ltd | Hold | — | $1.3M |
For informational purposes only. Not investment advice. Data: sec-api.io & SEC EDGAR 13F-HR filings. Duquesne Family Office LLC (Duquesne Family Office LLC) 13F filings are filed 45 days after quarter end — positions may have changed. Last updated: 2026-05-20.