Duquesne Family Office LLC Portfolio
Duquesne Family Office LLC manages Duquesne Family Office LLC, an institutional investment manager registered with the SEC (CIK: 1536411). Portfolio data sourced from Form 13F filings.
Duquesne Family Office LLC × Duquesne Family Office LLC
Portfolio structure and quarterly positioning at a glance.
concentration
Executing a significant $3.38 billion portfolio realignment, Duquesne Family Office LLC’s Q1 2026 13F filing revealed 68 distinct positions. Thirty new equities entered the allocation, signaling aggressive adjustments rather than minor tweaks to existing holdings. Concentration heavily skews toward top bets: NTRA commands 18.1%, EWZ holds 8.7%, INSM 5.6%, TSM 5.0%, and RSP 4.7%.
Duquesne Family Office LLC (Duquesne Family Office LLC) — Top 10 Holdings Q1 2026
| Stock | Weight | Activity | Shares Δ | Value |
|---|---|---|---|---|
 NTRA Natera Inc | Add +22% | +552K | $612.7M | |
EWZ Ishares Inc | Reduce −51% | −7.90M | $294.2M | |
INSM Insmed Inc | Reduce −22% | −328K | $188.7M | |
Taiwan Semiconductor Manufac | Reduce −9% | −48K | $167.4M | |
RSP Invesco Exchange Traded Fd T | Reduce −30% | −353K | $157.6M | |
YPF Ypf Sociedad Anonima | Add +433% | +2.63M | $149.6M | |
TBBB Bbb Foods Inc | Add +16% | +434K | $110.0M | |
Alcoa Corp | Add +9% | +117K | $99.1M | |
NAMS Newamsterdam Pharma Company | Hold | — | $98.3M | |
Sea Ltd | Add +17% | +156K | $91.1M |
Duquesne Family Office LLC’s Implied Market View — Q1 2026
Last Quarter Activity — Duquesne Family Office LLC (Duquesne Family Office LLC) Q1 2026
| Stock | Action | Shares Δ | Value | Wt. |
|---|---|---|---|---|
YPF Ypf Sociedad Anonima | Add +433% | +2.63M | $149.6M | 4.43% |
NTRA Natera Inc | Add +22% | +552K | $612.7M | 18.14% |
STM Stmicroelectronics N V | Add +238% | +1.84M | $90.3M | 2.67% |
Broadcom Inc | New Buy | +196K new | $60.6M | 1.8% |
ARGT Global X Fds | New Buy | +387K new | $36.2M | 1.07% |
CAI Caris Life Sciences Inc | New Buy | +1.89M new | $33.9M | 1.0% |
RVMD Revolution Medicines Inc | New Buy | +316K new | $30.7M | 0.91% |
Sandisk Corp | New Buy | +38K new | $24.2M | 0.72% |
QoQ change vs Dec 2025 filing.
| Stock | Action | Shares Δ | Value | Wt. |
|---|---|---|---|---|
EWZ Ishares Inc | Reduce −51% | −7.90M | $294.2M | 8.71% |
INSM Insmed Inc | Reduce −22% | −328K | $188.7M | 5.59% |
Taiwan Semiconductor Manufac | Reduce −9% | −48K | $167.4M | 4.96% |
RSP Invesco Exchange Traded Fd T | Reduce −30% | −353K | $157.6M | 4.67% |
WWD Woodward Inc | Reduce −64% | −380K | $75.6M | 2.24% |
TEVA Teva Pharmaceutical Inds Ltd | Reduce −60% | −3.50M | $71.6M | 2.12% |
AEVA AEVA Aeva Technologies Inc | Full Exit | Sold 100% | $24.2M | 0% |
GOOG GOOGL Alphabet Inc | Full Exit | Sold 100% | $120.5M | 0% |
AAL AAL American Airls Group Inc | Full Exit | Sold 100% | $9.8M | 0% |
AGX AGX Argan Inc | Full Exit | Sold 100% | $9.4M | 0% |
QoQ change vs Dec 2025 filing.
New Positions — Duquesne Family Office LLC (Duquesne Family Office LLC) Q1 2026
Duquesne Family Office LLC made significant new purchases in Q1 2026, allocating $60.6 million to Broadcom Inc. This move captures exposure to semiconductor infrastructure and enterprise software. Argentina’s equity market drew $36.2 million through the Global X MSCI Argentina ETF (ARGT), signaling a bet on economic recovery. Caris Life Sciences Inc received a $33.9 million allocation, reflecting a conviction in precision medicine and cancer diagnostics.
Duquesne’s Q1 activity reveals a dual focus: high-conviction technology and specific macro bets. Revolution Medicines Inc, a new $30.7 million position, expands the firm’s biotech exposure. Adding $24.2 million to Sandisk Corp reinforces a bet on data storage and memory solutions. Humana Inc, a $23.8 million addition, demonstrates an interest in managed healthcare. The firm actively seeks growth drivers across disparate sectors, from advanced semiconductors to emerging market equities and targeted medical innovation.
| Stock | Action | Value |
|---|---|---|
Broadcom Inc | New Buy | $60.6M |
| See AVGO analyst sentiment | ||
ARGT Global X Fds | New Buy | $36.2M |
CAI Caris Life Sciences Inc | New Buy | $33.9M |
RVMD Revolution Medicines Inc | New Buy | $30.7M |
Sandisk Corp | New Buy | $24.2M |
| See SNDK analyst sentiment | ||
HUM Humana Inc | New Buy | $23.8M |
TWLO Twilio Inc | New Buy | $22.9M |
Jabil Inc | New Buy | $21.8M |
| See JBL analyst sentiment | ||
GSG Ishares S&P Gsci Commodity- | New Buy | $20.7M |
Linde Plc | New Buy | $20.4M |
| See LIN analyst sentiment | ||
STX Seagate Technology Hldngs Pl | New Buy | $19.9M |
NUVB Nuvation Bio Inc | New Buy | $19.5M |
Intel Corp | New Buy | $18.2M |
| See INTC analyst sentiment | ||
BLTE Belite Bio Inc Sponsored | New Buy | $16.9M |
Arm Holdings Plc | New Buy | $16.1M |
| See ARM analyst sentiment | ||
OLMA Olema Pharmaceuticals Inc | New Buy | $14.7M |
Q Qnity Electronics Inc | New Buy | $14.5M |
XENE Xenon Pharmaceuticals Inc | New Buy | $13.9M |
JBS Jbs N.V. | New Buy | $11.8M |
NET Cloudflare Inc | New Buy | $10.8M |
LYB Lyondellbasell Industries Nv | New Buy | $10.6M |
VIST Vista Energy S.A.B. De C.V. | New Buy | $10.2M |
TWST Twist Bioscience Corp | New Buy | $9.8M |
COHR Coherent Corp | New Buy | $9.6M |
CLS Celestica Inc | New Buy | $9.4M |
DBVT Dbv Technologies S A Sponsored | New Buy | $8.0M |
Micron Technology Inc | New Buy | $7.9M |
| See MU analyst sentiment | ||
LITE Lumentum Hldgs Inc | New Buy | $4.9M |
SOLS Solstice Advanced Matls Inc | New Buy | $4.8M |
WLK Westlake Corporation | New Buy | $2.5M |
Increased Positions — Duquesne Family Office LLC (Duquesne Family Office LLC)
Duquesne Family Office added aggressively to existing positions during Q1 2026, confirming belief in specific names. Netzsch AG (NTRA) received a 22% bump, raising the firm’s stake to $612.7 million. Argentine oil producer YPF SA (YPF) saw the most dramatic increase; Duquesne expanded its holding by 433%, pushing the position to $149.6 million. This sharp acceleration in YPF demonstrates a renewed emphasis on the company.
Additional existing holdings also grew. Trinity Biotech PLC (TBBB) saw a 16% increase, with Duquesne’s position reaching $110.0 million. Alcoa Corp. (AA) grew by 9%, making the stake $99.1 million. Sea Ltd. (SE) also expanded, rising 17% to $91.1 million. These additions across multiple companies show Duquesne reinforcing its bets.
| Stock | Action | Value |
|---|---|---|
NTRA Natera Inc | Add +22% | $612.7M |
YPF Ypf Sociedad Anonima | Add +433% | $149.6M |
TBBB Bbb Foods Inc | Add +16% | $110.0M |
Alcoa Corp | Add +9% | $99.1M |
Sea Ltd | Add +17% | $91.1M |
STM Stmicroelectronics N V | Add +238% | $90.3M |
ROKU Roku Inc | Add +29% | $71.0M |
OPCH Option Care Health Inc | Add +7% | $50.3M |
SCCO Southern Copper Corp | Add +1% | $21.0M |
CLF Cleveland-Cliffs Inc New | Add +33% | $19.5M |
U Unity Software Inc | Add +80% | $16.2M |
ADMA Adma Biologics Inc | Add +513% | $13.9M |
Stocks Sold or Reduced — Duquesne Family Office LLC (Duquesne Family Office LLC) Q1 2026
Duquesne Family Office LLC significantly trimmed its holdings during Q1 2026, shedding exposure across several key positions. The institutional investment manager, registered with the SEC, cut its Ishares Inc (EWZ) stake by a sharp 51%. Woodward Inc (WWD) saw an even steeper reduction, down 64%, while Teva Pharmaceutical Inds Ltd (TEVA) experienced a 60% cut. These moves suggest a re-evaluation of specific sectors or geographies.
Further adjustments reshaped Duquesne’s portfolio composition. The firm reduced its position in Invesco Exchange Traded Fd T (RSP) by 30%, decreasing its broad market exposure. Insmed Inc (INSM) saw a 22% reduction. Taiwan Semiconductor Manufac (TSM) received the smallest cut among the reported reductions, down 9%. These actions reveal a tactical shift in allocation, selectively de-risking positions rather than initiating wholesale exits.
| Stock | Action | Δ Value | Shares Δ |
|---|---|---|---|
EWZ Ishares Inc | Reduce −51% | $294.2M | 7.90M |
INSM Insmed Inc | Reduce −22% | $188.7M | 328K |
Taiwan Semiconductor Manufac | Reduce −9% | $167.4M | 48K |
RSP Invesco Exchange Traded Fd T | Reduce −30% | $157.6M | 353K |
WWD Woodward Inc | Reduce −64% | $75.6M | 380K |
TEVA Teva Pharmaceutical Inds Ltd | Reduce −60% | $71.6M | 3.50M |
 Amazon Com Inc | Reduce −85% | $51.2M | 1.43M |
CPNG Coupang Inc | Reduce −61% | $50.4M | 4.11M |
CRH Crh Plc | Reduce −21% | $39.7M | 97K |
FIGR Figure Technology Solutio | Reduce −25% | $39.1M | 389K |
QSR Restaurant Brands Intl Inc | Reduce −62% | $33.6M | 755K |
LSCC Lattice Semiconductor Corp | Reduce −65% | $30.0M | 603K |
UAL United Airls Hldgs Inc | Reduce −25% | $24.2M | 86K |
WAB Wabtec | Reduce −68% | $23.7M | 205K |
IWM Ishares Tr | Reduce −65% | $19.6M | 147K |
BE Bloom Energy Corp | Reduce −82% | $18.5M | 604K |
DAKT Daktronics Inc | Reduce −34% | $11.0M | 290K |
STUB Stubhub Hldgs Inc | Reduce −41% | $8.5M | 939K |
PCT Purecycle Technologies Inc | Reduce −67% | $5.0M | 1.92M |
MELI Mercadolibre Inc | Reduce −94% | $4.8M | 44K |
Why Duquesne Family Office LLC’s (Duquesne Family Office LLC) Moves Matter
Duquesne Family Office LLC repositioned its holdings during Q1 2026, initiating 30 new investments. Natera (NTRA) became the largest position, accounting for 18.1% of the portfolio, a $612.7 million stake. The iShares MSCI Brazil ETF (EWZ) followed, taking 8.7% at $294.2 million. Insmed (INSM) comprised the third largest holding, 5.6% valued at $188.7 million. This investment pattern — a strong tilt toward specialized biotechnology firms and significant exposure to Brazilian equities — indicates a precise macro view: conviction in specific growth sectors and targeted international markets, rather than a generalized market bet.
Retail investors scrutinizing these Duquesne Family Office LLC filings gain insight into institutional strategy, not immediate buy signals. Managers submit Form 13F disclosures 45 days after quarter-end, meaning Q1 2026 data reflects decisions made up to March 31. This time lag makes replicating positions impractical for short-term gains. Duquesne Family Office LLC, an institutional investment manager, operates with extensive research capabilities; individual investors should use 13F data to understand professional investment processes and potential areas of interest, rather than as a trading guide.
About Duquesne Family Office LLC — Duquesne Family Office LLC
Duquesne Family Office LLC manages Duquesne Family Office LLC, an institutional investment manager registered with the SEC (CIK: 1536411). Portfolio data sourced from Form 13F filings.
- Manages Duquesne Family Office LLC — SEC-registered institutional investment manager
- CIK: 1536411 — Required to disclose equity holdings quarterly via Form 13F
Duquesne Family Office LLC (Duquesne Family Office LLC) — Complete Q1 2026 13F Holdings
| Stock | Weight | Activity | Shares Δ | Value |
|---|---|---|---|---|
NTRA Natera Inc | Add +22% | +552K | $612.7M | |
EWZ Ishares Inc | Reduce −51% | −7.90M | $294.2M | |
INSM Insmed Inc | Reduce −22% | −328K | $188.7M | |
Taiwan Semiconductor Manufac | Reduce −9% | −48K | $167.4M | |
RSP Invesco Exchange Traded Fd T | Reduce −30% | −353K | $157.6M | |
YPF Ypf Sociedad Anonima | Add +433% | +2.63M | $149.6M | |
TBBB Bbb Foods Inc | Add +16% | +434K | $110.0M | |
Alcoa Corp | Add +9% | +117K | $99.1M | |
NAMS Newamsterdam Pharma Company | Hold | — | $98.3M | |
Sea Ltd | Add +17% | +156K | $91.1M | |
STM Stmicroelectronics N V | Add +238% | +1.84M | $90.3M | |
WWD Woodward Inc | Reduce −64% | −380K | $75.6M | |
TEVA Teva Pharmaceutical Inds Ltd | Reduce −60% | −3.50M | $71.6M | |
ROKU Roku Inc | Add +29% | +167K | $71.0M | |
Broadcom Inc | New Buy | +196K new | $60.6M | |
SPY State Str Spdr S&P 500 Etf T | Hold | — | $58.5M | |
Amazon Com Inc | Reduce −85% | −1.43M | $51.2M | |
CPNG Coupang Inc | Reduce −61% | −4.11M | $50.4M | |
OPCH Option Care Health Inc | Add +7% | +123K | $50.3M | |
CRH Crh Plc | Reduce −21% | −97K | $39.7M | |
FIGR Figure Technology Solutio | Reduce −25% | −389K | $39.1M | |
ARGT Global X Fds | New Buy | +387K new | $36.2M | |
CAI Caris Life Sciences Inc | New Buy | +1.89M new | $33.9M | |
QSR Restaurant Brands Intl Inc | Reduce −62% | −755K | $33.6M | |
RVMD Revolution Medicines Inc | New Buy | +316K new | $30.7M | |
LSCC Lattice Semiconductor Corp | Reduce −65% | −603K | $30.0M | |
Sandisk Corp | New Buy | +38K new | $24.2M | |
UAL United Airls Hldgs Inc | Reduce −25% | −86K | $24.2M | |
HUM Humana Inc | New Buy | +138K new | $23.8M | |
WAB Wabtec | Reduce −68% | −205K | $23.7M | |
TWLO Twilio Inc | New Buy | +182K new | $22.9M | |
Jabil Inc | New Buy | +82K new | $21.8M | |
SCCO Southern Copper Corp | Add +1% | +1K | $21.0M | |
GSG Ishares S&P Gsci Commodity- | New Buy | +643K new | $20.7M | |
Linde Plc | New Buy | +41K new | $20.4M | |
STX Seagate Technology Hldngs Pl | New Buy | +51K new | $19.9M | |
IWM Ishares Tr | Reduce −65% | −147K | $19.6M | |
CLF Cleveland-Cliffs Inc New | Add +33% | +568K | $19.5M | |
NUVB Nuvation Bio Inc | New Buy | +4.54M new | $19.5M | |
BE Bloom Energy Corp | Reduce −82% | −604K | $18.5M | |
Intel Corp | New Buy | +411K new | $18.2M | |
BLTE Belite Bio Inc Sponsored | New Buy | +106K new | $16.9M | |
PTGX Protagonist Therapeutics Inc | Hold | — | $16.8M | |
U Unity Software Inc | Add +80% | +329K | $16.2M | |
Arm Holdings Plc | New Buy | +107K new | $16.1M | |
OLMA Olema Pharmaceuticals Inc | New Buy | +987K new | $14.7M | |
Q Qnity Electronics Inc | New Buy | +126K new | $14.5M | |
ADMA Adma Biologics Inc | Add +513% | +1.29M | $13.9M | |
XENE Xenon Pharmaceuticals Inc | New Buy | +239K new | $13.9M | |
JBS Jbs N.V. | New Buy | +656K new | $11.8M | |
DAKT Daktronics Inc | Reduce −34% | −290K | $11.0M | |
NET Cloudflare Inc | New Buy | +53K new | $10.8M | |
LYB Lyondellbasell Industries Nv | New Buy | +131K new | $10.6M | |
VIST Vista Energy S.A.B. De C.V. | New Buy | +135K new | $10.2M | |
TWST Twist Bioscience Corp | New Buy | +206K new | $9.8M | |
COHR Coherent Corp | New Buy | +40K new | $9.6M | |
CLS Celestica Inc | New Buy | +33K new | $9.4M | |
STUB Stubhub Hldgs Inc | Reduce −41% | −939K | $8.5M | |
DBVT Dbv Technologies S A Sponsored | New Buy | +383K new | $8.0M | |
Micron Technology Inc | New Buy | +23K new | $7.9M | |
SATS Echostar Corp | Hold | — | $7.1M | |
ALM Almonty Inds Inc | Hold | — | $6.8M | |
PCT Purecycle Technologies Inc | Reduce −67% | −1.92M | $5.0M | |
LITE Lumentum Hldgs Inc | New Buy | +7K new | $4.9M | |
MELI Mercadolibre Inc | Reduce −94% | −44K | $4.8M | |
SOLS Solstice Advanced Matls Inc | New Buy | +63K new | $4.8M | |
WLK Westlake Corporation | New Buy | +21K new | $2.5M | |
WVE Wave Life Sciences Ltd | Hold | — | $1.3M |
For informational purposes only. Not investment advice. Data: sec-api.io & SEC EDGAR 13F-HR filings. Duquesne Family Office LLC (Duquesne Family Office LLC) 13F filings are filed 45 days after quarter end — positions may have changed. Last updated: 2026-07-23.